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Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy (ATOM)
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Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures

Jessica Godin1, Yu-Hwa Lo

  • 1Department of Electrical and Computer Engineering, University of California, San Diego, 9500 Gilman Drive MC 0409, La Jolla, CA 92037, USA.

Biomedical Optics Express
|January 25, 2011
PubMed

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...