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A rare case of pleural lymphoma
Sumitra Basuthakur1, Anirban Sarkar, Sushanta Burman
1Professor, Dept.of TB & Respiratory Medicine, Medical College, 88, College Street, Kolkata.
Lung India : Official Organ of Indian Chest Society
|January 26, 2011
Summary
A young male presented with prolonged symptoms mimicking pleural effusion. Diagnostic imaging and biopsy revealed a high-grade, diffuse large B-cell non-Hodgkin lymphoma originating from the pleura.
Area of Science:
- Oncology
- Thoracic Medicine
- Diagnostic Cytopathology
Background:
- Non-Hodgkin lymphoma (NHL) can present with diverse extranodal manifestations.
- Pleural involvement by lymphoma, while uncommon, requires careful diagnostic consideration.
- Distinguishing lymphoma from other pleural pathologies like effusion or mesothelioma is crucial.
Purpose of the Study:
- To report a rare case of primary pleural non-Hodgkin lymphoma.
- To highlight the diagnostic challenges and imaging findings associated with pleural lymphoma.
- To emphasize the role of image-guided cytology in confirming the diagnosis.
Main Methods:
- Clinical presentation review including symptoms of fever, weight loss, and chest pain.
- Radiological assessment using Chest X-ray and Computed Tomography (CT) scan of the thorax.
- Diagnostic confirmation via CT-guided Fine Needle Aspiration Cytology (FNAC).
Main Results:
- The patient exhibited symptoms suggestive of left-sided pleural effusion.
- Imaging revealed a distinct pleura-based mass in the left hemithorax.
- FNAC definitively diagnosed high-grade, diffuse large B-cell type non-Hodgkin lymphoma.
Conclusions:
- Primary pleural lymphoma can present insidiously, mimicking more common pleural diseases.
- Integrated diagnostic approach involving clinical, radiological, and cytopathological evaluation is essential.
- CT-guided FNAC is a valuable tool for establishing the diagnosis of pleural lymphoma.
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