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Updated: Jun 4, 2026
07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Glaucoma anterior chamber morphometry based on optical Scheimpflug images.
Ruiz Simonato Alonso1, Renato Ambrósio Junior, Augusto Paranhos Junior
1Department of Ophthalmology, Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil. ruizsa@hotmail.com
Arquivos Brasileiros De Oftalmologia
|January 29, 2011
Summary
The Pentacam HR effectively identifies eyes at risk for angle closure using anterior chamber angle (ACA), volume (ACV), and depth (ACD) measurements. This noncontact method shows high specificity in detecting narrow angles, aiding in glaucoma screening.
Area of Science:
- Ophthalmology
- Medical Imaging
- Glaucoma Research
Background:
- Accurate evaluation of the anterior chamber angle (ACA) is crucial for diagnosing and managing glaucoma.
- Traditional gonioscopy is subjective and can be time-consuming.
- Noncontact anterior segment imaging offers a potentially more objective and efficient alternative.
Purpose of the Study:
- To compare the diagnostic performance of gonioscopy with noncontact anterior chamber tomography (High Resolution Pentacam - HR) using optical Scheimpflug images.
- To evaluate the ability of the Pentacam HR in assessing anterior chamber angle (ACA) measurements.
- To determine the efficacy of Pentacam HR in identifying eyes at risk for angle closure.
Main Methods:
- A transversal study involving 112 eyes from 74 subjects was conducted.
- Gonioscopy was performed and graded using the Shaffer Classification (SC).
- Pentacam HR imaging was used to obtain automated measurements of ACA, anterior chamber volume (ACV), and anterior chamber depth (ACD).
Main Results:
- Gonioscopy classified 60.07% of eyes as open-angle and 33.93% as narrow-angle.
- Pentacam HR measurements showed significantly different ACA, ACV, and ACD between open-angle and narrow-angle groups (p<0.001 for ACV, p<0.0001 for ACD).
- Receiver Operating Characteristic (ROC) curve analysis demonstrated 52.6% sensitivity and 100% specificity for Pentacam HR in screening eyes with ACA ≤ 20º (SC Grade 2).
Conclusions:
- The Pentacam HR, utilizing optical Scheimpflug imaging, is capable of assessing anterior chamber dimensions.
- The system demonstrated significant differences in ACV and ACD between open and narrow angles.
- Pentacam HR shows promise in detecting eyes at risk for angle closure by analyzing ACV and ACD, with high specificity.
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