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Basophil Activation Test for Allergy Diagnosis
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Quantification of specific IgE to whole peanut extract and peanut components in prediction of peanut allergy
The Journal of Allergy and Clinical Immunology
|January 29, 2011
Abstract
No abstract available in PubMed .
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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...