Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Oxygen Delivering System I: Nasal Cannula and Face Mask

Oxygen Delivering System I: Nasal Cannula and Face Mask

The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Systemic glucocorticoid activity in extremely preterm neonates after antenatal betamethasone and intratracheal budesonide: a sub-study of the PLUSS trial.

Journal of perinatology : official journal of the California Perinatal Association·2026

Same author

Rethinking parenteral nutrition as supportive therapy for neonatal sepsis.

Med (New York, N.Y.)·2026

Same author

Continuous glucose monitoring in neonates at risk of hypoglycaemia: a feasibility study.

Archives of disease in childhood. Fetal and neonatal edition·2026

Same author

High-Flow Nasal Cannula and Continuous Positive Airway Pressure in Infants With Acute Bronchiolitis-Trends of Use in Norway.

Acta paediatrica (Oslo, Norway : 1992)·2026

Same author

CoNS blood culture isolates from very preterm infants: antibiotic susceptibility, synergy testing and <i>mecA</i> gene expression.

JAC-antimicrobial resistance·2026

Same author

Probiotics for extremely preterm infants: a Norwegian population-based study.

Archives of disease in childhood. Fetal and neonatal edition·2026

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

Laryngeal Mask Airway (LMA) Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway (SGA)

Laryngeal Mask Airway (LMA) Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway (SGA)

Published on: July 14, 2023

Sustained inflations: comparing three neonatal resuscitation devices.

Claus Klingenberg¹, Jennifer A Dawson, Angela Gerber

¹Department of Paediatrics, University Hospital of North Norway, Tromsø, Norway. claus.klingenberg@unn.no

|January 29, 2011

Summary

Achieving sustained inflations for neonatal resuscitation is challenging with self-inflating bags, often falling short of the recommended 10 seconds. A T-piece device offers more consistent pressure delivery for these critical procedures.

More Related Videos

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Related Experiment Videos

Last Updated: Jun 4, 2026

Laryngeal Mask Airway (LMA) Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway (SGA)

Laryngeal Mask Airway (LMA) Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway (SGA)

Published on: July 14, 2023

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Area of Science:

Neonatal Resuscitation
Pediatric Emergency Medicine
Respiratory Care

Background:

National resuscitation guidelines suggest 2-3 second sustained inflations for infants.
Longer inflation times (≥10 seconds) are used for preterm infants.

Purpose of the Study:

To evaluate the capacity of clinicians with varying experience levels to deliver sustained inflations.
To compare the performance of three distinct manual ventilation devices during sustained inflations.

Main Methods:

Fifty clinical staff members used a self-inflating bag, flow-inflating bag, or T-piece device.
Target: 10-second sustained inflation with 30 cm H2O peak pressure.
Measurements included peak inflating pressure (PIP), mean inflating pressure (MIP), and duration of pressure above 20 and 25 cm H2O.

Main Results:

The T-piece and flow-inflating bag achieved median inflation durations >10 seconds (10.7s and 10.6s, respectively).
Self-inflating bags resulted in significantly shorter inflation durations (2.5s).
Operator experience showed a weak correlation with longer inflation times only for self-inflating bags.

Conclusions:

The T-piece device provided consistent peak pressure with less variation during 10-second sustained inflations compared to the flow-inflating bag.
Sustained inflations exceeding 3 seconds were difficult to achieve using a self-inflating bag.