Related Experiment Video
Updated: Jun 4, 2026
05:31
Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
Brewing the right cocktail for radial intervention
1Victoria Heart Institute, Victoria, British Columbia, Canada. tvuurmans@vhif.org
Indian Heart Journal
|February 1, 2011
Summary
Transradial coronary angiography uses a radial artery approach for less complications. A combination of heparin, nitroglycerin, and verapamil effectively prevents radial artery occlusion and spasm.
Area of Science:
- Cardiology
- Vascular Surgery
- Interventional Radiology
Background:
- Radial access angioplasty is increasingly preferred globally for reduced complications, enhanced mobility, and cost-effectiveness.
- While generally safe due to collateral circulation, radial artery occlusion and spasm can occur, impacting patient comfort and procedure success.
- Existing pharmacological and non-pharmacological methods aim to prevent these complications, but optimal strategies remain debated.
Purpose of the Study:
- To review current literature and identify the most effective strategy for preventing radial artery occlusion and spasm during transradial procedures.
- To determine the optimal pharmacological 'cocktail' for pre-procedural administration.
Main Methods:
- Systematic review of relevant studies evaluating prevention strategies for radial artery occlusion and spasm.
- Analysis of pharmacological and non-pharmacological interventions used before transradial coronary angiography and angioplasty.
Main Results:
- A pre-procedural 'cocktail' of agents is recommended for preventing radial artery complications.
- The combination of heparin, nitroglycerin, and verapamil demonstrated the most favorable preventive outcomes in the reviewed studies.
Conclusions:
- The optimal strategy for preventing radial artery occlusion and spasm involves a multi-agent pharmacological approach.
- A heparin, nitroglycerin, and verapamil combination is associated with the best preventive results in transradial interventions.
More Related Videos
08:17A Semi-automated Approach to Preparing Antibody Cocktails for Immunophenotypic Analysis of Human Peripheral Blood
Published on: February 8, 2016
09:12Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method
Published on: May 19, 2023
Related Concept Videos
01:11Radical Reactivity: Overview
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired molecule. These three...
01:10Radical Reactivity: Steric Effects
The presence of electron-donating, electron-withdrawing, or conjugating groups adjacent to a radical center, imparts electronic stabilization to the radicals. Examples of such electronically-stabilized radicals are triphenylmethyl, tetramethylpiperidine‐N‐oxide, and 2,2‐diphenyl‐1‐picrylhydrazyl. These radicals are remarkably stable and are known as persistent radicals. Some of the persistent radicals can even be isolated and purified.
Along with electronic factors, steric factors also account...
Along with electronic factors, steric factors also account...
01:25Microbes in Beverage Production
Alcoholic beverages such as wine, beer, and spirits are the products of microbial fermentation processes that transform simple sugars into ethanol and a wide array of complex flavor compounds. These transformations rely on the metabolic activities of specific yeasts and bacteria, which are selected and controlled to yield the desired beverage characteristics.Wine Fermentation and MaturationWine production begins with the crushing of grapes to release juice and pulp, forming a must that is...
01:03Radical Formation: Overview
A bond can be broken either by heterolytic bond cleavage to form ions or homolytic bond cleavage to yield radicals. A fishhook arrow is used to represent the motion of a single electron in homolytic bond cleavage. There are two main sources from which radicals can be formed:
Radicals from spin-paired molecules:
Radicals can be obtained from spin-paired molecules either by homolysis or electron transfer. While two radicals are formed in the former, an electron is added in the latter, also known...
Radicals from spin-paired molecules:
Radicals can be obtained from spin-paired molecules either by homolysis or electron transfer. While two radicals are formed in the former, an electron is added in the latter, also known...
01:33Radical Reactivity: Intramolecular vs Intermolecular
Radical reactions can occur either intermolecularly or intramolecularly. In an intermolecular radical reaction, a nucleophilic radical adds to an electrophilic alkene or vice versa. In such reactions, the radical and generally the alkene, which is also called the radical trap, are two different molecules. Additionally, for such intermolecular reactions to occur, the radical trap must be active, present in an excess concentration, and the radical starting material must have a weak carbon–halogen...
01:11Assessment of radial pulse
Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps: