Related Experiment Video
Updated: Jun 4, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Balloon-facilitated delivery of a left ventricular pacing lead
Claude S Elayi1, Matthew G Whitbeck, Gustavo Morales
1Gill Heart Institute and Division of Cardiovascular Medicine, University of Kentucky, Lexington, Kentucky 40536-0200, USA. claude.elayi@uky.edu
Abstract:
While modern implant tools have contributed greatly to the success of cardiac resynchronization therapy, technical challenges remain. A common problem is the inability to advance left ventricular pacing leads into branch veins that are tortuous or arise at steep angles. In these cases, advancement of the lead causes it to buckle and prolapse into the coronary sinus or great cardiac vein. Lead prolapsed can be avoided by employing a balloon to temporarily obstruct the coronary sinus or great cardiac vein just upstream from the branch vein. The balloon redirects the force of advancement laterally into the branch vein, facilitating delivery.

