Related Experiment Video
Updated: Jun 4, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
Published on: March 3, 2021
Hypothermia: novel approaches for premature infants
Rosemary D Higgins1, Seetha Shankaran
1Pregnancy and Perinatology Branch, Center for Developmental Biology and Perinatal Medicine, NICHD, NIH 6100 Executive Blvd, Room 4B03B MSC 7510 Bethesda, MD 20892, USA. higginsr@mail.nih.gov
Abstract:
Hypothermia for hypoxic ischemic encephalopathy has recently permeated clinical practice for term infants. Speculation regarding a neuroprotective benefit of hypothermia for premature infants with HIE has been raised as a need for further research. Hypothermia for other indications including necrotizing enterocolitis with the hope of tissue preservation following injury is less well studied. A summary of evidence for hypothermia and premature infants is presented in this brief report.
Related Concept Videos
Decreased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Factors Affecting Body Temperature
Factors may include:

