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Updated: Jun 4, 2026

11:55
Examining the Conformational Dynamics of Membrane Proteins in situ with Site-directed Fluorescence Labeling
Published on: May 29, 2011
A fluorescent molecular ruler as a selective probe for ω-aminoacids
Daniel Moreno1, José V Cuevas, Gabriel García-Herbosa
1Departamento de Química, Facultad de Ciencias, Universidad de Burgos, 09001 Burgos, Spain.
Abstract:
A fluorescent probe for ω-aminoacids behaves as a molecular ruler, changing the yellow fluorescent emission into blue as a function of the distance between the terminal ammonium and the carboxylate groups, permitting the quantitative detection of ω-aminoacids, their metabolites and related drugs, such as pregabalin or gabapentin, from pharmaceutical formulations.

