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Acute stent thrombosis associated with heparin-induced thrombocytopenia and abciximab-induced profound

Tarun W Dasari1, Reji Pappy, Thomas A Hennebry

  • 1920 Stanton L. Young Blvd., WP 3010, Cardiovascular Section, OUHSC, Oklahoma City, OK 73190, USA. dasaritarun@gmail.com

The Journal of Invasive Cardiology
|February 8, 2011
PubMed

Heparin-induced thrombocytopenia (HIT) is a wellknown complication after exposure to heparin products. Profound thrombocytopenia has also been reported with the use of abciximab, a glycoprotein IIb/IIIa receptor antagonist, which is used during percutaneous coronary intervention. Acute stent thrombosis is a rare but serious complication of HIT. We report an unusual case of acute stent thrombosis with concomitant heparin- and abciximab-induced profound thrombocytopenia and discuss the subsequent treatment strategies. Prompt identification and management of this disorder is critically important to avoid devastating complications.

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