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Published on: June 13, 2025
The obesity epidemic and disordered sleep during childhood and adolescence
David Gozal1, Leila Kheirandish-Gozal
1Section of Pediatric Sleep Medicine, Department of Pediatrics, Pritzker School of Medicine, University of Chicago, 5721 S. Maryland Avenue, MC 8000, Suite K-160, Chicago, IL 60637, USA. dgozal@uchicago.edu
Insights
Childhood obesity is rising globally, potentially impacting health and longevity. This chapter explores the links between sleep and obesity, including obstructive sleep apnea, and their combined health effects.
Area of Science:
- Pediatrics
- Public Health
- Sleep Medicine
Background:
- The global prevalence of childhood obesity is increasing at an alarming rate.
- The long-term health implications of this trend are significant, potentially affecting life expectancy.
- Emerging research suggests a connection between sleep patterns and obesity in children.
Purpose of the Study:
- To critically evaluate the evidence linking sleep and childhood obesity.
- To review the bidirectional relationship between obesity and obstructive sleep apnea (OSA).
- To examine how obesity and OSA exacerbate each other's pathophysiology and associated morbidities.
Main Methods:
- Literature review of existing studies on sleep and obesity.
- Analysis of research on the interplay between obesity and obstructive sleep apnea.
- Examination of the amplification of comorbidities in affected children.
Main Results:
- Evidence supporting a link between sleep disturbances and childhood obesity is growing.
- Obesity is a significant risk factor for obstructive sleep apnea.
- Obstructive sleep apnea can worsen metabolic dysfunction and contribute to obesity.
Conclusions:
- The relationship between sleep, obesity, and obstructive sleep apnea is complex and bidirectional.
- Addressing sleep issues may be crucial in managing childhood obesity.
- Further research is needed to fully elucidate these interrelationships and develop effective interventions.
Abstract:
The obesity pandemic is claiming its presence even among youngest of children and is clearly on the rise. Although the extent and implications of this massive increase in the prevalence of overweight and obese children are unclear, they are anticipated to be deleterious to global health outcomes and life expectancy. The potential interrelationships between sleep and obesity have gained recent attention. In this chapter, we initially examine the critical evidence supporting or refuting such proposed associations. In addition, the potential reciprocal roles of obesity and obstructive sleep apnea in the facilitation of their pathophysiology are also reviewed, along with their amplificatory effects on their respective morbidities.
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