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5-oxo-15-HETE: total synthesis and bioactivity

Pranav Patel1, Jaganmohan R Anumolu, William S Powell

  • 1Claude Pepper Institute, Florida Institute of Technology, Melbourne, FL 32901, USA.

Bioorganic & Medicinal Chemistry Letters
|February 15, 2011
PubMed
Summary

Researchers achieved the first total synthesis of 6(E),8(Z),11(Z),13(E) 5-oxo-15-HETE. This synthetic compound was tested for its ability to mobilize calcium, comparing it to the natural OXE receptor ligand, 5-oxo-ETE.

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