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Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
Published on: February 1, 2019
Lyophilization of nonviral gene delivery systems
1P. R. Pharmaceuticals, Ft. Collins, CO.
Methods in Molecular Medicine
|February 15, 2011
Abstract:
This chapter presents a qualitative description of the freeze-drying process as it pertains to the development of stable, dry polycation-DNA complex formulations. It is not intended to be a comprehensive treatise on freeze-drying. Readers are referred to a series of excellent papers by Pikal (1-5) for more detailed, quantitative explanations of the freeze-drying process.
