Related Experiment Video
Updated: Jun 4, 2026
14:24
Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
Intracordal injection technique: materials and injection site
Etsuyo Tamura1, Hiroyuki Fukuda, Yasuhiko Tabata
1Department of Otorhinolaryngology, Tokai University School of Medicine, Tokai University Tokyo Hospital, 1-2-5 Yoyogi, Shibuya-ku, Tokyo, Japan. otamura@tok.u-tokai.ac.jp
The Tokai Journal of Experimental and Clinical Medicine
|February 15, 2011
Summary
Choosing the right vocal cord injection material and site is crucial for effective vocal rehabilitation. Proper selection based on the cause of glottal dysfunction improves outcomes for patients with voice disorders.
Area of Science:
- Otolaryngology
- Speech Science
- Biomaterials
Background:
- Intracordal injections are used to treat glottal closure deficiencies.
- Optimal injection sites and materials vary depending on the specific condition.
Purpose of the Study:
- To review vocal cord injection sites and materials.
- To determine suitable materials and injection sites for different laryngeal diseases based on vocal cord structure and material characteristics.
Main Methods:
- Analysis of injection materials used in Japan.
- Consideration of vocal cord anatomy.
- Correlation of material properties and injection sites with disease types.
Main Results:
- Type I collagen (commercial or autologous fascia) injected superficially disturbs vocal cord mucosal wave motion; deeper injection is recommended.
- Fat tissue injection does not disturb mucosal wave motion and is effective for vocal cord atrophy or sulcus vocalis.
- Collagen injection is indicated for unilateral recurrent laryngeal nerve paralysis.
Conclusions:
- Material and site selection for intracordal injection in vocal rehabilitation should be guided by the specific cause of glottal dysfunction.
- Tailoring the injection approach optimizes treatment for various voice disorders.
