Related Experiment Video
Updated: Jul 21, 2026

07:26
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Our challenge in oral pathology
1School of Dentistry, University of Alabama, Birmingham.
Summary
Oral pathology, a specialty since the 1940s, faces challenges in diagnosing oral and facial diseases. Differentiating benign from malignant conditions is crucial due to unique head and neck factors.
Area of Science:
- Oral pathology
- Head and neck oncology
Background:
- Oral pathology emerged as a distinct medical specialty in the 1940s.
- Significant diagnostic and treatment difficulties characterized oral and facial diseases during the specialty's inception.
- The head and neck region exhibits unique embryonic and histogenetic properties influencing disease patterns.
Purpose of the Study:
- To discuss the complexities and challenges encountered by oral pathology specialists.
- To highlight the importance of distinguishing between benign and malignant oral and facial diseases.
Main Methods:
- This article is a discussion-based review.
- It synthesizes current understanding of oral and facial disease challenges.
Main Results:
- Distinguishing benign from malignant oral and facial lesions remains a critical aspect of oral pathology.
- Unique anatomical and developmental factors in the head and neck contribute to disease complexity.
Conclusions:
- Oral pathology specialists confront ongoing challenges in disease diagnosis and management.
- Understanding the unique biological factors of the head and neck is essential for effective oral pathology practice.
Related Concept Videos
Oral Cavity
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Tooth Anatomy
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Assessment of the Mouth
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

