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Updated: Jun 4, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

Acral soft tissue tumors: a review.

Dipti Mahajan1, Steven D Billings, John R Goldblum

  • 1Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA.

Advances in Anatomic Pathology
|February 18, 2011
PubMed
Summary

Acral soft tissue tumors pose diagnostic challenges. This review covers common benign and malignant tumors in acral locations, detailing clinical, histologic, and immunohistochemical features for diagnosis and prognosis.

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Area of Science:

  • Dermatopathology
  • Oncology
  • Surgical Pathology

Background:

  • Acral soft tissue tumors present unique diagnostic difficulties for clinicians and pathologists.
  • Understanding these tumors is crucial for accurate diagnosis and effective patient management.

Purpose of the Study:

  • To review common benign and malignant soft tissue tumors found in acral locations.
  • To provide a comprehensive overview of their clinical, histologic, and immunohistochemical characteristics.
  • To aid in differential diagnosis and prognosis assessment.

Main Methods:

  • Literature review of common acral soft tissue tumors.
  • Synthesis of clinical presentation data.
  • Analysis of histologic and immunohistochemical findings.

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A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
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Last Updated: Jun 4, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

Published on: July 28, 2020

  • Review of prognostic indicators and differential diagnostic criteria.

    • Main Results:

    • Detailed discussion of frequently encountered benign acral tumors (e.g., glomus tumors, hemangiomas).
    • Comprehensive overview of malignant acral tumors (e.g., squamous cell carcinoma, melanoma, sarcomas).
    • Emphasis on distinguishing features, immunohistochemistry, and prognostic factors for each entity.

    Conclusions:

    • Acral soft tissue tumors require careful evaluation due to overlapping features.
    • Integrated analysis of clinical, histologic, and immunohistochemical data is essential for accurate diagnosis.
    • This review serves as a guide for managing these challenging neoplasms.