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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
Published on: March 27, 2020
Yin Yang 1: a multifaceted protein beyond a transcription factor
Zhiyong Deng1, Paul Cao, Mei Mei Wan
1Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Abstract:
As a transcription factor, Yin Yang 1 (YY1) regulates the transcription of a dazzling list of genes and the number of its targets still mounts. Recent studies revealed that YY1 possesses functions independent of its DNA binding activity and its regulatory role in tumorigenesis has started to emerge.
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