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Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

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Functional dyspepsia is associated with sleep disorders.

Brian E Lacy1, Kelly Everhart, Michael D Crowell

  • 1Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA. brian.lacy@hitchcock.org

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
|February 22, 2011
PubMed
Summary

Functional dyspepsia (FD) is linked to poor sleep quality. Patients with FD, especially those with severe symptoms, experience more sleep disturbances and anxiety.

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Area of Science:

  • Gastroenterology
  • Sleep Medicine
  • Psychiatry

Background:

  • Functional dyspepsia (FD) is a common gastrointestinal disorder.
  • Sleep disturbances are frequently reported in individuals with FD.
  • The relationship between sleep quality, FD severity, and psychological well-being requires further investigation.

Purpose of the Study:

  • To evaluate sleep quality in patients diagnosed with functional dyspepsia.
  • To quantify the association between disordered sleep, FD symptom severity, and mental and physical health.
  • To compare sleep patterns and psychological status between FD patients and healthy controls.

Main Methods:

  • 131 adult FD patients meeting Rome III criteria and 50 healthy controls were enrolled.
  • Participants completed questionnaires assessing demographics, lifestyle, anxiety, depression, overall health, sleep quality, and insomnia severity.
  • Multivariate logistic regression was used to identify factors associated with disordered sleep.

Main Results:

  • FD patients exhibited higher scores for anxiety and depression compared to controls.
  • Moderate to severe FD symptoms correlated with significantly poorer sleep quality and increased insomnia severity.
  • Disordered sleep was independently associated with functional dyspepsia (OR, 3.25) and female sex (OR, 2.36).

Conclusions:

  • Functional dyspepsia is significantly associated with disordered sleep.
  • Sleep disturbances in FD patients are linked to symptom severity and elevated anxiety levels.
  • Further research is warranted to explore the causal relationship between sleep problems and FD symptoms.