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Frailty in the critically ill: a novel concept
Robert C McDermid1, Henry T Stelfox, Sean M Bagshaw
1Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3C1.12 Walter C Mackenzie Centre, 8440-112 ST NW, Edmonton, Canada T6G 2B7.
Frailty, a syndrome of declining reserve, may apply to critically ill patients, similar to older adults. Measuring frailty in intensive care units (ICUs) could predict outcomes and guide treatment decisions.
Area of Science:
- Gerontology
- Critical Care Medicine
- Clinical Epidemiology
Background:
- Frailty is a syndrome of decreased reserve and increased vulnerability, linked to aging and comorbid conditions.
- The frail phenotype involves declines in mobility, muscle mass, nutrition, strength, and endurance.
- Critically ill patients may share similarities with frail geriatric patients, with potential implications for outcomes.
Purpose of the Study:
- To explore the concept of frailty in critically ill patients.
- To investigate the potential clinical relevance and predictive value of frailty in intensive care unit (ICU) settings.
- To highlight the need for studies on frailty's correlation with outcomes and resource utilization in critical care.
Main Methods:
- Conceptual analysis comparing frailty in geriatric and critically ill populations.
- Review of trends in ICU resource utilization by older adults.
- Hypothesized need for objective frailty measurement in critical care.
Main Results:
- The prevalence of frailty in critically ill patients is unknown but likely increasing.
- Frailty may interact with illness severity, comorbidities, and socio-environmental factors.
- Objective frailty measurement could aid clinicians in end-of-life decision-making.
Conclusions:
- Frailty may be a relevant concept in critical care, analogous to its role in geriatrics.
- Further research is needed to validate frailty assessment and its impact on outcomes in critically ill patients.
- Frailty assessment could support clinical decisions regarding intensive care unit (ICU) support and life-sustaining therapies.
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