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Assessment of HPV infection among female university students in Honduras via Roche linear array
Annabelle Ferrera1, Nelba Tábora, Yensi Flores
1School of Microbiology, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras. f_annabelle@hotmail.com
Objective:
To determine the prevalence of specific types of human papillomavirus (HPV), and the association with possible risk factors, among female university students at university in Honduras.
Methods:
In a cross-sectional study, cervical samples from 400 women aged 18-35years were tested using a Roche HPV linear array to differentiate 37 genotypes of HPV. Associations with risk factors were assessed.
Results:
Of the 400 participants, 393 completed the study. HPV DNA was detected in 45% of these women, of whom 73% were infected with high-risk types of HPV and 46% had multiple infections. Overall, 36 HPV genotypes were identified, of which HPV types 16, 51, 84, 66, and 39 were the most common. There was a marked decrease in the prevalence of multiple and high-risk infections with age. The factors that were independently associated with risk of being infected were related to sexual behavior and smoking habits.
Conclusion:
The study showed that genital HPV infection is common among sexually active women at university in Honduras. In addition, the Roche linear array was shown to be a valuable tool for HPV genotyping, which will be useful for monitoring the future effectiveness of an HPV vaccine in the population.
