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Bilateral angle-closure glaucoma in a young female receiving cabergoline: a case report
Hasan Razmjoo1, Leila Rezaei, Alireza Dehghani
1Isfahan University of Medical Sciences and Health Services, Isfahan, Iran.
Case Reports in Ophthalmology
|February 25, 2011
Summary
Oral cabergoline, used for galactorrhea, can cause acute angle-closure glaucoma. This drug-induced glaucoma involves elevated intraocular pressure and refractive shifts, resolving after medication cessation.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Cabergoline is a dopamine agonist commonly prescribed for hyperprolactinemic disorders, including galactorrhea.
- Drug-induced glaucoma is a known, albeit uncommon, adverse effect of various medications.
Observation:
- A patient developed bilateral acute angle-closure glaucoma and myopic refractive error within hours of taking oral cabergoline for galactorrhea.
- Diagnostic imaging, including ultrasound biomicroscopy, revealed ciliary body effusion and anterior iris-ciliary body rotation.
Findings:
- Discontinuation of cabergoline and topical anti-glaucoma drops led to a reduction in intraocular pressure within 8 hours.
- The patient's refractive errors normalized within 8 days of treatment cessation.
Implications:
- This case highlights a potential ocular adverse effect of oral cabergoline, emphasizing the need for ophthalmologic awareness.
- Clinicians should consider cabergoline as a potential cause of acute angle-closure glaucoma in patients presenting with relevant symptoms.
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