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Retrieving HapMap Data via Bulk Download.

Albert Vernon Smith

|March 2, 2011

Summary

This summary is machine-generated.

The International Haplotype Map Project created a comprehensive human genome map detailing genetic variations. This resource accelerates disease gene discovery and is publicly accessible for research.

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Area of Science:

Genomics
Human Genetics
Bioinformatics

Background:

The International Haplotype Map Project aimed to map common human genetic variations.
Understanding these variations is crucial for identifying genes linked to diseases.
Previous efforts laid the groundwork for large-scale genotyping.

Purpose of the Study:

To develop a comprehensive haplotype map of the human genome.
To provide a resource for accelerating the discovery of genetic causes of human disease.
To detail common patterns of genetic variation across populations.

Main Methods:

Genotyping of approximately 3.9 million single-nucleotide polymorphisms (SNPs).
Analysis of data from 270 individuals across four worldwide populations.

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Data compilation and preparation for public release.

Main Results:

Creation of a detailed haplotype map of the human genome.
Identification of millions of distinct single-nucleotide polymorphisms (SNPs).
Data made available for unrestricted public use via the HapMap Web site.

Conclusions:

The HapMap data significantly advances the search for genetic disease causes.
The publicly accessible dataset facilitates broad scientific research.
Bulk download protocols are described for accessing the complete dataset.