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Related Experiment Videos

Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.

M E McNamara1, B S Fogel

  • 1Psychiatric Medical Clinic, Rhode Island Hospital, Providence 02903.

The Journal of Neuropsychiatry and Clinical Neurosciences
|January 1, 1990
PubMed
Summary
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Recurrent panic attacks may be triggered by subtle focal cortical discharges, mimicking epilepsy. Anticonvulsant therapy and electroencephalography may benefit patients with refractory panic attacks.

Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Panic attacks and complex partial seizures share overlapping symptoms, making differential diagnosis challenging.
  • Distinguishing between panic attacks and seizures is crucial for appropriate treatment.

Observation:

  • Five patients presented with recurrent panic attacks and temporal lobe electroencephalogram (EEG) abnormalities.
  • These patients did not meet criteria for a clinical diagnosis of partial seizures.

Findings:

  • All five patients responded favorably to anticonvulsant therapy.
  • The findings suggest focal cortical discharges may precipitate panic attacks in some individuals.
  • An unequivocal diagnosis of epilepsy was not established in these cases.

Implications:

Related Experiment Videos

  • Electroencephalography (EEG) and trials of anticonvulsant medication should be considered for panic attack patients unresponsive to standard treatments.
  • This approach may identify a subset of panic disorder patients with underlying subclinical epileptic activity.