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Updated: Jun 4, 2026

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
Published on: June 2, 2019
A pain in the leg following angiography
Mark P Ainslie1, John Macdonald, J Smyth
1Royal Salford Hospital, Hope Hospital, Stott Lane, Manchester, United Kingdom. markpeterainslie@hotmail.com
Abstract:
This case illustrates a complication following deployment of the Angioseal® vascular closure device after routine angiography. The AngioSeal device is a percutaneous, bioabsorbable, collagen-based hemostatic plug deployed to seal the arterial puncture. We describe a 69-year-old gentleman who presented with unilateral leg cramps 1 week post-procedure. When seen in the cardiology clinic, a magnetic resonance imaging angiogram was requested, which showed a filling defect in the right popliteal artery. The collagen seal had embolized and was subsequently removed by the vascular surgeons.
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