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Related Experiment Video

Updated: Jun 4, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

[Disaccharide intolerance].

Nedeljko Radlović

Srpski Arhiv Za Celokupno Lekarstvo

|March 4, 2011

Summary

Disaccharide intolerance, often due to enzyme deficits, causes digestive issues like diarrhea or bloating. Diagnosis involves overload tests or genetic analysis, with treatment focusing on elimination diets.

Area of Science:

Gastroenterology and Human Metabolism

Context:

Disaccharide intolerance is a complex condition arising from primary or secondary enzyme deficiencies.
It can also result from absorption disorders or issues with monomer metabolism.

Purpose:

To elucidate the heterogeneous nature of disaccharide intolerance.
To describe its varied clinical presentations based on age and severity.
To outline diagnostic and therapeutic strategies.

Summary:

Clinical symptoms range from osmotic-fermentative diarrhea in infants to abdominal colic and bloating in older individuals.
Metabolic forms manifest as hypoglycemic crises and multisystemic damage.
Diagnosis relies on overload tests for gastrointestinal forms and enzyme/genetic defect confirmation for metabolic types.

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Impact:

Highlights the importance of accurate diagnosis for effective management.
Emphasizes the role of elimination diets in treating disaccharide intolerance.
Underscores the need to address underlying conditions in secondary forms.