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Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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DNA fusion vaccines against B-cell tumors

D Zhu1, M B Spellerberg, C A King

  • 1Molecular Immunology Group, Tenovus Research Laboratory, Southampton University Hospitals Trust, Southampton, UK.

Methods in Molecular Medicine
|March 5, 2011
PubMed

The ability of naked DNA to induce immune responses against encoded antigen has been clearly demonstrated for infectious diseases (1). In many cases, the induced immunity is able to protect against infection, and can approach the efficacy of exogenous antigen (2).

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