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Updated: Jun 3, 2026

Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment
Published on: January 6, 2026
Multiframe image super-resolution adapted with local spatial information
Liangpei Zhang1, Qiangqiang Yuan, Huanfeng Shen
1The State Key Laboratory of Information Engineering in Surveying, Mapping and Remote Sensing, Wuhan University, China.
Abstract:
Super-resolution image reconstruction, which has been a hot research topic in recent years, is a process to reconstruct high-resolution images from shifted, low-resolution, degraded observations. Among the available reconstruction frameworks, the maximum a posteriori (MAP) model is widely used. However, existing methods usually employ a fixed prior item and regularization parameter for the entire HR image, ignoring local spatially adaptive properties, and the large computation load caused by the solution of the large-scale ill-posed problem is another issue to be noted. In this paper, a block-based local spatially adaptive reconstruction algorithm is proposed. To reduce the large computation load and realize the local spatially adaptive process of the prior model and regularization parameter, first the target image is divided into several same-sized blocks and the structure tensor is used to analyze the local spatial properties of each block. Different property prior items and regularization parameters are then applied adaptively to different properties' blocks. Experimental results show that the proposed method achieves better performance than methods with a fixed prior item and regularization parameter.
