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Related Experiment Videos

Changes in human skin blood flow by hyperthermia.

C W Song1, L M Chelstrom, D J Haumschild

  • 1University of Minnesota Medical School, Department of Therapeutic Radiology-Radiation Oncology, Minneapolis, MN 55455.

International Journal of Radiation Oncology, Biology, Physics
|April 1, 1990
PubMed
Summary

Heating human skin significantly increases blood flow by up to 20 times. This study reveals previously unknown arteriovenous anastomoses in forearm skin, challenging existing physiological views.

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Area of Science:

  • Physiology
  • Dermatology
  • Biomedical Engineering

Background:

  • Human forearm skin's microcirculation and vascular structures are not fully understood.
  • The presence of arteriovenous anastomoses in forearm skin is debated.

Purpose of the Study:

  • To investigate heat-induced changes in human forearm skin blood circulation.
  • To assess the role of arterioles, capillaries, and potential arteriovenous anastomoses in regulating blood flow during thermal stimulation.

Main Methods:

  • Noninvasive monitoring of red blood cell velocity and volume using laser Doppler flowmetry (LDF).
  • Controlled heating of forearm skin surface to temperatures ranging from 35°C to 43°C for 60 minutes.

Main Results:

Related Experiment Videos

  • Laser Doppler flow (LDF) demonstrated dynamic changes, with blood flow increasing up to 15-20 times at 43°C.
  • Increased blood flow was attributed to arteriolar dilation, capillary recruitment, and enhanced red blood cell velocity.
  • Elevated red cell flux velocity suggests the presence of arteriovenous anastomoses in human forearm skin.

    • Conclusions:

    • Human forearm skin exhibits significant, dynamic increases in blood flow in response to heat.
    • The findings indicate the presence of arteriovenous anastomoses in human forearm skin, contrary to previous assumptions.
    • Laser Doppler flowmetry is an effective tool for studying microcirculatory responses in skin.