Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulse Oximetry01:24

Pulse Oximetry

1.0K
Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
1.0K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

230
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
230
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

14.0K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
14.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determining Barriers to Dietary Change Among Medically Underserved Men With Prostate Cancer.

Health education & behavior : the official publication of the Society for Public Health Education·2026
Same author

Height-based formulas for predicting intravascular length of tunnelled neck central venous catheter in paediatric population.

Pediatric surgery international·2023
Same author

A strongly inhomogeneous superfluid in an iron-based superconductor.

Nature·2019
Same author

Site-Specific and Coherent Manipulation of Individual Qubits in a 1D Optical Lattice with a 532-nm Site Separation.

Physical review letters·2019
Same author

Amplifier for scanning tunneling microscopy at MHz frequencies.

The Review of scientific instruments·2018
Same author

Barriers to physical activity and healthy diet among breast cancer survivors: A multilevel perspective.

European journal of cancer care·2017
Same journal

Mammalian Respiratory Chain Complex Assemblies and Their Links to Mitochondria Stress-Induced Human Diseases.

Advances in experimental medicine and biology·2026
Same journal

Enzyme Assemblies in Nucleotide Metabolism: Structure, Regulation, and Disease Implications.

Advances in experimental medicine and biology·2026
Same journal

The Pyruvate Dehydrogenase Complex: A 90-Year-Old Enigma Shaping the Future of Structural Enzymology.

Advances in experimental medicine and biology·2026
Same journal

Regulation of the Anti-termination RNA Transcription Complex by Lon-Mediated Lambda N Degradation.

Advances in experimental medicine and biology·2026
Same journal

PCNA Macromolecular Complexes: PCNA Serves as a Molecular Hub Regulating Multiple Cellular Processes Inside and Outside of the Nucleus.

Advances in experimental medicine and biology·2026
Same journal

Dynamic Assemblies in Genome Maintenance.

Advances in experimental medicine and biology·2026
See all related articles

Related Experiment Video

Updated: Nov 6, 2025

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
14:28

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Published on: May 10, 2024

1.9K

Scanning Tissue Oxygen Needle Probe.

S Ashkenazi1,2, D Cho3, C W Song3

  • 1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA. ashke003@umn.edu.

Advances in Experimental Medicine and Biology
|May 9, 2021
PubMed
Summary
This summary is machine-generated.

A novel needle-based probe enables optical scanning of tissue oxygen partial pressure without mechanical translation, minimizing tissue damage. This innovation offers new possibilities for research and clinical applications.

Keywords:
Oxygen sensorPhosphorescenceTissue oxygen scanningpO2 profile

More Related Videos

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
09:56

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

11.0K
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

9.0K

Related Experiment Videos

Last Updated: Nov 6, 2025

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
14:28

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Published on: May 10, 2024

1.9K
Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
09:56

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

11.0K
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

9.0K

Area of Science:

  • Biomedical Engineering
  • Medical Devices
  • Optical Sensing

Background:

  • Accurate measurement of tissue oxygen partial pressure is crucial for understanding physiological processes and diagnosing diseases.
  • Existing methods for tissue oxygen scanning often involve mechanical needle translation, which can cause significant tissue damage and limit repeated measurements.
  • There is a need for less invasive and more precise methods to assess oxygen levels within biological tissues.

Purpose of the Study:

  • To introduce a new device for scanning oxygen partial pressure along a line within biological tissue.
  • To present a novel probe design that avoids mechanical translation within the tissue during scanning.
  • To detail the device's design, characterization, and potential applications in research and clinical settings.

Main Methods:

  • The device features a stainless-steel needle probe with an active sensing area along its shaft.
  • An internal optical fiber is used to optically scan the sensing area, allowing for line-based oxygen measurements.
  • The system incorporates optical scanning, a unique sensing mechanism, mechanical design, and signal processing for data acquisition.

Main Results:

  • The paper details the device's design, including its sensing mechanism, mechanical and optical configurations, and signal processing.
  • Characterization and testing results of the device are presented, demonstrating its performance.
  • The device allows for repeated optical scans along a line without needle movement, thereby reducing tissue trauma.

Conclusions:

  • The developed device offers a less invasive approach to measuring tissue oxygen partial pressure.
  • This technology has potential applications in various research fields, including physiology and pathology.
  • The device could aid in clinical diagnoses and monitoring treatment efficacy by providing precise oxygen level data.