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Related Experiment Videos

Changes in human skin blood flow by hyperthermia.

C W Song1, L M Chelstrom, D J Haumschild

  • 1University of Minnesota Medical School, Department of Therapeutic Radiology-Radiation Oncology, Minneapolis, MN 55455.

International Journal of Radiation Oncology, Biology, Physics
|April 1, 1990
PubMed
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Heating human skin significantly increases blood flow by up to 20 times. This study reveals previously unknown arteriovenous anastomoses in forearm skin, challenging existing physiological views.

Area of Science:

  • Physiology
  • Dermatology
  • Biomedical Engineering

Background:

  • Human forearm skin's microcirculation and vascular structures are not fully understood.
  • The presence of arteriovenous anastomoses in forearm skin is debated.

Purpose of the Study:

  • To investigate heat-induced changes in human forearm skin blood circulation.
  • To assess the role of arterioles, capillaries, and potential arteriovenous anastomoses in regulating blood flow during thermal stimulation.

Main Methods:

  • Noninvasive monitoring of red blood cell velocity and volume using laser Doppler flowmetry (LDF).
  • Controlled heating of forearm skin surface to temperatures ranging from 35°C to 43°C for 60 minutes.

Main Results:

Related Experiment Videos

  • Laser Doppler flow (LDF) demonstrated dynamic changes, with blood flow increasing up to 15-20 times at 43°C.
  • Increased blood flow was attributed to arteriolar dilation, capillary recruitment, and enhanced red blood cell velocity.
  • Elevated red cell flux velocity suggests the presence of arteriovenous anastomoses in human forearm skin.

    • Conclusions:

    • Human forearm skin exhibits significant, dynamic increases in blood flow in response to heat.
    • The findings indicate the presence of arteriovenous anastomoses in human forearm skin, contrary to previous assumptions.
    • Laser Doppler flowmetry is an effective tool for studying microcirculatory responses in skin.