Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Synthetic Biology

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...

Drug Absorption Mechanism: Carrier-Mediated Membrane Transport

Drug Absorption Mechanism: Carrier-Mediated Membrane Transport

Certain large, lipid-insoluble drug molecules that resemble amino acids, peptides, or glucose, require specialized carrier proteins to facilitate their diffusion across cell membranes. This transport can occur through either facilitated diffusion, which does not require energy input, or active transport, which does require energy input.
Facilitated diffusion is a passive process that utilizes human Solute Carrier (SLC) transporters. These transporters bind to the drug, undergo structural...

Short-distance Transport of Resources

Short-distance Transport of Resources

Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.

Secondary Active Transport

Secondary Active Transport

One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme "pump" embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...

Secondary Active Transport

Secondary Active Transport

One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme "pump" embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...

Secondary Active Transport

Secondary Active Transport

One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme “pump” embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Light and Dark Cycles Control the Structural Evolution of Photoresponsive Supramolecular Systems.

Angewandte Chemie (International ed. in English)·2026

Same author

Synthesis of Soft Octahedral Nanoparticles through Supramolecular Self-Assembly of <i>C</i><sub>3</sub>-Symmetric Trinaphthylamine Trisamides.

Journal of the American Chemical Society·2026

Same author

Ion-Pair Breakers and Anionic Brønsted Acids for Helmholtz-Layer Catalysis with External Electric Fields in Microfluidic Capacitors.

JACS Au·2026

Same author

Flipper dendrimers.

Chemical science·2026

Same author

3D self-assembly of cyclic peptides into multilayered nanosheets.

Chemical science·2026

Same author

2D Assemblies Based on a Tetraphenylethylene D,L-Cyclic Peptide Scaffold.

Angewandte Chemie (International ed. in English)·2025

Same journal

Fluorescent merocyanines: from fundamental properties to applications as molecular probes, in bioimaging and as emissive dye aggregates.

Chemical Society reviews·2026

Same journal

Direct impure water electrolysis at industrial scale.

Chemical Society reviews·2026

Same journal

Catalytic valorization of polyolefins: from catalysts and processes to reactors.

Chemical Society reviews·2026

Same journal

Designing stable π-radicals.

Chemical Society reviews·2026

Same journal

Antibacterial drug discovery: challenges and preclinical promises from synthetic small molecules.

Chemical Society reviews·2026

Same journal

Selective carbon-carbon bond cleavage involving alkene moieties.

Chemical Society reviews·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 3, 2026

Construction of Out-of-Equilibrium Metabolic Networks in Nano- and Micrometer-Sized Vesicles

Construction of Out-of-Equilibrium Metabolic Networks in Nano- and Micrometer-Sized Vesicles

Published on: April 12, 2024

Recent synthetic transport systems.

Stefan Matile¹, Andreas Vargas Jentzsch, Javier Montenegro

¹Department of Organic Chemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch

Chemical Society Reviews

|March 11, 2011

Summary

This summary is machine-generated.

Researchers reviewed advances in synthetic ion channels and pores from 2006-2009. New interactions like metal-organic and anion-π bonds drove significant breakthroughs in these artificial transport systems.

More Related Videos

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

Published on: October 6, 2019

Cell-Free Protein Synthesis System for Building Synthetic Cells

Cell-Free Protein Synthesis System for Building Synthetic Cells

Published on: April 19, 2024

Related Experiment Videos

Last Updated: Jun 3, 2026

Construction of Out-of-Equilibrium Metabolic Networks in Nano- and Micrometer-Sized Vesicles

Construction of Out-of-Equilibrium Metabolic Networks in Nano- and Micrometer-Sized Vesicles

Published on: April 12, 2024

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

Published on: October 6, 2019

Cell-Free Protein Synthesis System for Building Synthetic Cells

Cell-Free Protein Synthesis System for Building Synthetic Cells

Published on: April 19, 2024

Area of Science:

Supramolecular Chemistry
Materials Science
Chemical Biology

Background:

Synthetic transport systems mimic biological ion channels and pores.
Previous reviews in this series covered progress up to 2005.
The field has seen significant advancements in design and function.

Purpose of the Study:

To provide a comprehensive review of synthetic ion channels and pores.
To highlight progress made between January 2006 and December 2009.
To cover a broad range of structural and functional motifs.

Main Methods:

Literature review of scientific publications from 2006-2009.
Analysis of structural and functional data from synthetic systems.
Categorization of new interaction types driving progress.

Main Results:

Significant breakthroughs in synthetic ion channel and pore development.
Expansion of interaction types utilized, including metal-organic, π-π, and anion-π interactions.
Incorporation of dynamic covalent bonds in system design.

Conclusions:

The field of synthetic transport systems has advanced rapidly due to novel interactions.
These advancements offer potential applications in various chemical and biological contexts.
The review provides a valuable resource for chemists and materials scientists.