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Fixed drug eruptions occurring on the male genitals
1Dermatology Department, Hamad Medical Corporation, Doha, Qatar, Arabian Gulf.
Cutis
|April 1, 1990
Summary
Fixed drug eruptions can affect only the male genitalia, with cotrimoxazole being the most frequent culprit. The glans penis is the most commonly affected site in these localized cases.
Area of Science:
- Dermatology
- Urology
Background:
- Fixed drug eruptions (FDEs) are a specific type of adverse drug reaction.
- Genital involvement in FDEs is uncommon and often overlooked.
Purpose of the Study:
- To describe cases of FDEs exclusively affecting the male genitalia.
- To identify the drugs and specific anatomical locations involved.
Main Methods:
- Retrospective case series.
- Analysis of 28 patients with genital FDEs.
Main Results:
- Twenty-eight cases of FDEs limited to the male genitalia were identified.
- Cotrimoxazole was the most frequently implicated drug.
- The glans penis was the most commonly affected anatomical site.
Conclusions:
- FDEs can present solely on the male genitalia.
- Clinicians should consider FDEs in patients with genital lesions after drug exposure, particularly to cotrimoxazole.