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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Accessory Structures of the Skin: Hair and Hair Follicles01:16

Accessory Structures of the Skin: Hair and Hair Follicles

Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Flexural and extensoral eruptions in dermatologic disease.

Zain Husain1, Philip J Cohen, Robert A Schwartz

  • 1Department of Dermatology, UMDNJ-New Jersey Medical School, 185 South Orange Avenue, Medical Science Building Room C520, Newark, NJ 07103-2714, USA.

Clinics in Dermatology
|March 15, 2011
PubMed
Summary

Recognizing patterns of dermatologic eruptions on flexure and extensor surfaces can help diagnose skin conditions. This study focuses on identifying specific skin lesions affecting these body areas.

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Area of Science:

  • Dermatology
  • Clinical Pathology

Background:

  • Dermatologic eruptions present with diverse clinical patterns.
  • Localized eruptions can indicate specific underlying pathologies.
  • Understanding lesion distribution is key for diagnosis.

Purpose of the Study:

  • To discuss dermatologic lesions affecting flexure and extensor surfaces.
  • To highlight the diagnostic significance of lesion localization.

Main Methods:

  • Review of dermatologic literature.
  • Analysis of clinical patterns of skin lesions.
  • Focus on lesions affecting flexural and extensor areas.

Main Results:

  • Specific dermatologic eruptions exhibit characteristic distributions.
  • Flexural and extensor surfaces are common sites for certain skin conditions.
  • Pattern recognition aids in differential diagnosis.

Conclusions:

  • The location of dermatologic lesions provides crucial diagnostic clues.
  • Understanding patterns on flexure and extensor surfaces enhances diagnostic accuracy.
  • Clinical pattern analysis is fundamental in dermatologic diagnosis.