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Increased Body Temperature

Increased Body Temperature

A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.

Types of Fever

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
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Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

Seizures: Classification

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
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Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

Seizures l: Introduction

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...

Seizures ll: Types

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Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...

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Related Experiment Video

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Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits

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Febrile seizures.

Leena D Mewasingh¹

¹Imperial College Healthcare NHS Trust, London, UK.

BMJ Clinical Evidence

|March 17, 2011

Summary

This summary is machine-generated.

Simple febrile seizures in children are common and generally harmless, with no long-term cognitive or behavioral effects. Treatments during fever episodes or long-term anticonvulsants do not appear to prevent future epilepsy.

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Area of Science:

Pediatrics
Neurology

Background:

Simple febrile seizures affect 2-9% of children globally by age 5.
These seizures are generalized, brief (<15 minutes), and non-recurrent within 24 hours.
They do not negatively impact behavior, cognition, or academic performance.

Purpose of the Study:

To evaluate treatments for simple febrile seizures in children.
To assess the efficacy of long-term anticonvulsant therapy in preventing subsequent epilepsy.
To review interventions for fever episodes and their impact on seizure recurrence.

Main Methods:

Systematic review of 18 studies including systematic reviews, RCTs, and observational studies.
Searched major databases (Medline, Embase, Cochrane Library) up to March 2010.
Included safety alerts from regulatory agencies (FDA, MHRA).

Main Results:

Evidence quality was assessed using the GRADE system.
Information was gathered on anticonvulsants (intermittent/continuous) and antipyretics (physical, paracetamol, ibuprofen).

Conclusions:

This review synthesizes evidence on the effectiveness and safety of various interventions for simple febrile seizures.
The findings inform clinical decisions regarding the management of febrile seizures in children.