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Fatigue in psoriasis with arthritis.

Claudio Carneiro1, Mario Chaves, Gustavo Verardino

  • 1Sector of Dermatology and Post-Graduation Course in Dermatology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

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Summary

Fatigue is a common symptom in chronic diseases like psoriatic arthritis, impacting physical, emotional, and cognitive well-being. Understanding its complex causes is crucial for patient management.

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Area of Science:

  • Immunology
  • Rheumatology
  • Dermatology

Background:

  • Fatigue is a prevalent and complex symptom associated with numerous chronic diseases, including cancer and various neurologic, metabolic, and psychiatric conditions.
  • It is influenced by disease activity, medication, demographics, and symptom duration, manifesting across physical, emotional, cognitive, and social domains.
  • Fatigue often coexists with and is exacerbated by mood disturbances, anemia, infections, pain, sleep issues, and stress, complicating its assessment.

Purpose of the Study:

  • To explore the multifaceted nature of fatigue in chronic diseases.
  • To investigate the specific impact of psoriatic arthritis on physical function, psychological well-being, and quality of life.
  • To identify fatigue as a common somatic manifestation in psoriatic arthritis.

Main Methods:

  • Literature review on fatigue in chronic diseases.
  • Analysis of patient-reported outcomes in psoriatic arthritis.
  • Correlation of disease-specific factors with fatigue and quality of life.

Main Results:

  • Fatigue significantly impacts patients with chronic diseases, affecting multiple life dimensions.
  • Psoriatic arthritis patients exhibit reduced physical activity due to joint pain and inflammation.
  • Common manifestations in psoriatic arthritis include decreased self-esteem, depression, reduced quality of life, and significant fatigue and sleep disturbances.

Conclusions:

  • Fatigue is a critical, multidimensional symptom in chronic inflammatory conditions like psoriatic arthritis.
  • The physical and psychological burden of psoriatic arthritis contributes significantly to fatigue and sleep disturbances.
  • Further research is needed to develop targeted interventions for fatigue in psoriatic arthritis patients.