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The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Assessment measures in systemic lupus erythematosus
Eutília Andrade Medeiros Freire1, Laís Medeiros Souto, Rozana Mesquita Ciconelli
1Universidade Federal da Paraíba. eutilia@terra.com.br
Revista Brasileira De Reumatologia
|March 18, 2011
Summary
This review identifies key assessment measures for systemic lupus erythematosus (SLE), focusing on disease activity, damage, and quality of life. Patient-reported outcomes are crucial for evaluating health status and treatment impact in SLE patients.
Area of Science:
- Rheumatology
- Autoimmune Diseases
- Clinical Assessment
Background:
- Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease affecting multiple organ systems.
- Diagnosis and management rely on clinical and laboratory parameters.
- Comprehensive assessment is vital for effective patient care.
Purpose of the Study:
- To conduct an integrative literature review of assessment measures for SLE.
- To identify and categorize existing methods for evaluating SLE.
- To explore domains of SLE assessment including disease activity, damage, and quality of life.
Main Methods:
- Bibliographic research using LILACS, MEDLINE/PubMed, and SCIELO databases.
- Search terms included "assessment and lupus," "quality of life and lupus," "damage and lupus," "activity index and lupus," and "patient outcomes and lupus."
- Integrative review methodology was employed.
Main Results:
- Three primary domains of SLE assessment were identified: disease activity, disease-induced damage, and quality of life.
- Various measures exist within these domains for evaluating SLE.
- Patient-reported outcomes significantly contribute to assessing health status.
Conclusions:
- The study highlights the importance of multidimensional assessment in SLE.
- Patient perception of health status and quality of life are key indicators.
- Utilizing proposed assessment measures can enhance the evaluation of SLE impact and treatment effectiveness.
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