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Updated: Jun 3, 2026
08:12
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral valved stent implantation: an overview.
Tim Attmann1, Saskia Pokorny, Lucian Lozonschi
1Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Summary
This study introduces a novel self-expanding mitral valved stent for minimally invasive implantation. The mitral valved stent demonstrated reproducible deployment, stability, and adequate function in acute and short-term settings.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Interventional Cardiology
Background:
- Transcatheter valve implantation is currently restricted to pulmonary and aortic valve replacements.
- Minimally invasive mitral valve interventions are an area of active research and development.
Purpose of the Study:
- To analyze the feasibility and performance of a novel self-expanding valved stent for transapical mitral valve implantation.
- To evaluate stent positioning, function, and hemodynamic effects in an experimental setting.
Main Methods:
- A self-expanding mitral valved stent was designed for transapical implantation.
- Thirty pigs underwent off-pump mitral valved stent implantation with follow-up up to seven days.
- Transesophageal echocardiography and computed tomography were used for evaluation.
Main Results:
- Accurate positioning was achieved in most animals, and precise deployment reduced paravalvular leakage.
- No stent migration, embolization, or left ventricular outflow tract obstruction was observed.
- Minimal transvalvular gradients and adequate stent function were confirmed in acute and short-term follow-up.
Conclusions:
- The self-expanding mitral valved stent can be reproducibly deployed.
- The device shows potential for reliable stability, minimal left ventricular outflow tract gradients, and adequate function.
- This represents a promising approach for minimally invasive mitral valve replacement in experimental settings.
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