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Papulosquamous dermatoses of AIDS
N S Sadick1, N S McNutt, M H Kaplan
1Department of Medicine (Dermatology), Cornell University Medical College, New York Hospital, NY 10021.
Journal of the American Academy of Dermatology
|June 1, 1990
Summary
Human immunodeficiency virus (HIV) infection can cause various papulosquamous skin disorders. This review covers conditions like psoriasis and ichthyosis, exploring their links to immunosuppression.
Area of Science:
- Dermatology
- Infectious Diseases
- Immunology
Background:
- Papulosquamous disorders are common in patients with human immunodeficiency virus (HIV) infection.
- These skin conditions can range from xerosis generalisata to erythroderma.
- Understanding these dermatoses is crucial for managing HIV-infected individuals.
Purpose of the Study:
- To review the spectrum of papulosquamous disorders associated with HIV infection.
- To discuss specific conditions including seborrheic dermatitis, psoriasis, and acquired ichthyosis.
- To explore the pathogenesis and relationship of these disorders to HIV-induced immunosuppression.
Main Methods:
- Literature review of papulosquamous disorders in HIV-infected patients.
- Discussion of clinical presentations and histopathological findings.
- Analysis of proposed pathogenetic mechanisms.
Main Results:
- HIV infection is associated with a wide range of papulosquamous eruptions.
- Conditions such as psoriasis and pityriasis rosea-like eruptions may be more severe or atypical in HIV patients.
- Underlying immunosuppression plays a significant role in the development and presentation of these disorders.
Conclusions:
- Papulosquamous disorders represent a significant dermatological manifestation of HIV infection.
- Pathogenesis often involves complex interactions between the virus, immune system dysregulation, and potential co-infections.
- Recognition and appropriate management of these skin conditions are essential components of comprehensive HIV care.