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Published on: January 18, 2018
Advances in endovascular treatment of critical limb ischemia
Bryan P Yan1, Darragh Moran, Brian G Hynes
1Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital & Institute of Vascular Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Insights
Critical limb ischemia (CLI), a severe form of peripheral arterial disease, often leads to amputation without prompt treatment. Endovascular revascularization is now the preferred approach for CLI, particularly below-the-knee disease.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Peripheral Arterial Disease Management
Background:
- Critical limb ischemia (CLI) is the most severe clinical outcome of peripheral arterial disease (PAD).
- CLI poses a significant risk of mortality and limb amputation if not treated promptly.
- Endovascular revascularization has emerged as a primary treatment strategy for CLI.
Purpose of the Study:
- To review recent advancements in endovascular treatment options for CLI.
- To specifically highlight innovations in treating below-the-knee (BTK) arterial disease in CLI patients.
Main Methods:
- Review of current literature on endovascular techniques and devices for CLI.
- Focus on percutaneous approaches for below-the-knee interventions.
Main Results:
- Endovascular revascularization is increasingly the preferred primary treatment for CLI.
- Technological and procedural advancements have broadened eligibility for endovascular CLI treatment.
- Significant progress has been made in treating complex below-the-knee arterial lesions.
Conclusions:
- Endovascular therapy offers expanding options for CLI patients, especially for below-the-knee disease.
- Ongoing innovation in endovascular technology continues to improve treatment outcomes for CLI.
Abstract:
Critical limb ischemia (CLI) represents the most severe clinical manifestation of peripheral arterial disease. In the absence of timely revascularization, CLI carries high risk of mortality and amputation. Over the past decade, endovascular revascularization has rapidly become the preferred primary treatment strategy for CLI, especially for the treatment of below-the-knee disease. Advances in percutaneous devices and techniques have expanded the spectrum of patients with CLI who are deemed candidates for revascularization. This review will focus on advances in endovascular options for the treatment of CLI, in particular for below-the-knee disease.
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