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Induction of Accelerated Atherosclerosis in Mice: The "Wire-Injury" Model
Published on: August 25, 2020
First Report of Intentional Intraplaque Lithotripsy After Aggressive Wire Recanalization in Calcified Atheroma and
Jeffrey C Y Lee1, Timothy H H Kam2, Yasunari Sakamoto3
1Cardiac Medical Unit, Grantham Hospital, Hong Kong.
Abstract:
Eccentric calcified plaque remains a challenge in the endovascular treatment of peripheral arterial disease despite technological advancements. The "aggressive wire recanalization in calcified atheroma and dilatation" technique was invented to overcome this by intentional intraplaque wiring followed by atherectomy; however, distal embolization can ensue. Substitution with intravascular lithotripsy may be safer and equally effective. To the best of our knowledge, we performed the first case of intentional intraplaque lithotripsy to successfully treat a claudicant patient with heavily calcified bilateral superficial femoral arteries without complications. This may be considered a new technique variation to treat eccentric calcium.
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