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Related Concept Videos

Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Renewal of Intestinal Stem Cells01:23

Renewal of Intestinal Stem Cells

The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the goblet,...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...

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Catheterization of Intestinal Loops in Ruminants
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Published on: June 11, 2009

Recurrent intussusception in infants.

Frances A Justice1, Liem T Nguyen, Son N Tran

  • 1Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia.

Journal of Paediatrics and Child Health
|March 26, 2011
PubMed
Summary
This summary is machine-generated.

Recurrence of intussusception (IS) in infants is a concern, with a 14% risk within six months of a primary episode. This study highlights the natural history of recurrent IS, aiding vaccine surveillance interpretation.

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Area of Science:

  • Pediatric Gastroenterology
  • Clinical Pediatrics
  • Epidemiology

Background:

  • Clinical features predicting intussusception (IS) recurrence in infants are not well-defined.
  • Understanding recurrence risk is crucial for clinical management and public health initiatives.

Purpose of the Study:

  • To identify clinical features associated with increased risk of intussusception recurrence in infants.
  • To describe the natural history of recurrent intussusception.

Main Methods:

  • Prospective study of infants under 2 years with acute intussusception (IS) at the National Hospital of Pediatrics, Hanoi.
  • Included clinical presentation, treatment, and outcomes over 14 months.
  • Retrospective medical record review for complete patient ascertainment.

Main Results:

  • Recruited 598 infants; 53 (9%) had recurrent episodes.
  • Estimated 6-month recurrence risk after a primary episode was 14%.
  • Pathological lead points were rare; most cases treated successfully with enema reduction.

Conclusions:

  • The study provides insights into the natural history of recurrent intussusception in infants.
  • Findings may help interpret post-marketing surveillance data for rotavirus vaccines.
  • Further research can refine risk identification for recurrent intussusception.