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Recurrent intussusception in infants

Frances A Justice1, Liem T Nguyen, Son N Tran

  • 1Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia.

Journal of Paediatrics and Child Health
|March 26, 2011
PubMed

Insights

Recurrence of intussusception (IS) in infants is a concern, with a 14% risk within six months of a primary episode. This study highlights the natural history of recurrent IS, aiding vaccine surveillance interpretation.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Pediatrics
  • Epidemiology

Background:

  • Clinical features predicting intussusception (IS) recurrence in infants are not well-defined.
  • Understanding recurrence risk is crucial for clinical management and public health initiatives.

Purpose of the Study:

  • To identify clinical features associated with increased risk of intussusception recurrence in infants.
  • To describe the natural history of recurrent intussusception.

Main Methods:

  • Prospective study of infants under 2 years with acute intussusception (IS) at the National Hospital of Pediatrics, Hanoi.
  • Included clinical presentation, treatment, and outcomes over 14 months.
  • Retrospective medical record review for complete patient ascertainment.

Main Results:

  • Recruited 598 infants; 53 (9%) had recurrent episodes.
  • Estimated 6-month recurrence risk after a primary episode was 14%.
  • Pathological lead points were rare; most cases treated successfully with enema reduction.

Conclusions:

  • The study provides insights into the natural history of recurrent intussusception in infants.
  • Findings may help interpret post-marketing surveillance data for rotavirus vaccines.
  • Further research can refine risk identification for recurrent intussusception.
Abstract

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