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In Vitro Differentiation of Naive CD4+ T Cells into Pathogenic Th17 Cells in Mouse
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TGF-β in Th17 cell development: the truth is out there

Robin D Hatton1

  • 1Department of Pathology, University of Alabama, Birmingham, AL 35294, USA. rdzialo@uab.edu

Immunity
|March 26, 2011
PubMed
Summary

Gutcher et al. show that autocrine transforming growth factor-beta (TGF-β) cytokine is crucial for the development and maintenance of T helper 17 (Th17) cells. This finding advances understanding of immune cell differentiation.

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