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Related Concept Videos

Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Gross Anatomy of the Stomach01:16

Gross Anatomy of the Stomach

The human stomach is a vital part of the digestive system, performing multiple functions. It is located within the peritoneum, a serous membrane that lines the abdominal cavity. The stomach plays a central role in processing food substances and interacts with other digestive organs through coordinated digestive processes. The stomach has a characteristic J-shape and is divided into four main regions. The cardia is the first section where the esophagus connects to the stomach and is the entry...
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...

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Related Experiment Video

Updated: Jun 3, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
05:30

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

Stomach cancer.

Charles Bailey1

  • 1Kent and Sussex Hospital, Tunbridge Wells, Kent, UK.

BMJ Clinical Evidence
|March 29, 2011
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates surgical resection and adjuvant chemotherapy for stomach cancer. It synthesizes evidence on radical versus conservative surgery and chemotherapy

Related Experiment Videos

Last Updated: Jun 3, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
05:30

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer

Published on: October 31, 2025

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Stomach cancer, primarily adenocarcinoma, includes gastro-oesophageal junction tumors.
  • Incidence varies globally, with higher rates in Japanese men compared to British men.

Purpose of the Study:

  • To systematically review the effects of radical versus conservative surgical resection for stomach cancer.
  • To evaluate the efficacy and safety of adjuvant chemotherapy in stomach cancer treatment.

Main Methods:

  • Conducted a systematic review of Medline, Embase, and The Cochrane Library up to April 2010.
  • Included 19 systematic reviews, randomized controlled trials (RCTs), and observational studies.
  • Performed GRADE evaluation for evidence quality and included harms alerts from regulatory agencies.

Main Results:

  • Synthesized evidence on various interventions for resectable distal stomach tumors.
  • Evaluated effectiveness and safety of adjuvant chemoradiotherapy and chemotherapy.
  • Assessed lymphadenectomy (radical, conservative) and organ removal procedures.

Conclusions:

  • Presents information on the effectiveness and safety of surgical and chemotherapeutic interventions for stomach cancer.
  • Provides a basis for clinical decision-making regarding treatment strategies for resectable distal tumors.