Estimators and confidence intervals for the proportion using binary auxiliary information with applications to pharmaceutical studies
Related Experiment Video
Updated: Jun 3, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
1Department of Statistics and Operational Research, University of Granada, Granada, Spain. mrueda@ugr.es
Abstract:
Estimation of a proportion is commonly used in areas such as medicine, biopharmaceutical experiments, etc. Estimation of a proportion using auxiliary information has not been investigated in the literature. Ratio estimators of the population proportion and two-sided confidence intervals based upon auxiliary information are derived in this paper. Real data extracted from the Spanish National Health Survey are used to demonstrate the application of the proposed methods in the estimation of prevalences. Results derived from simulation studies show that proposed estimators are more efficient than the traditional estimator. Proposed confidence intervals outperform the alternative methods, especially in terms of interval width. A study on patients with hypertension is also considered to calculate various estimators and confidence intervals.
Related Concept Videos
Confidence Intervals
A confidence...
Interpretation of Confidence Intervals
Confidence intervals have confidence coefficients that are crucial for their interpretation. The most common confidence coefficients are 0.90, 0.95, and 0.99, which can be written as percentages–90%, 95%, and 99%, respectively.
Suppose a person calculates a confidence interval with a confidence coefficient of 0.95. In that case, they can...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Distributions to Estimate Population Parameter
Confidence Coefficient
Testing a Claim about Population Proportion
There are two methods of testing a claim about a population proportion: (1) Using the sample proportion from the data where a binomial distribution is approximated to the normal distribution and (2) Using the binomial probabilities calculated from the data.
The first method uses normal distribution as an approximation to the binomial distribution. The requirements are as follows: sample size is large...
