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Updated: Jun 3, 2026

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Published on: December 5, 2025

Microneedles and their applications.

Vishal Sachdeva¹, Ajay K Banga

¹Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Mercer University, Atlanta, GA 30341, USA.

Recent Patents on Drug Delivery & Formulation

|April 2, 2011

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Microneedle technology creates tiny skin channels for enhanced drug delivery, particularly for large molecules like proteins. This minimally invasive approach is advancing transdermal delivery for various therapeutic applications.

Area of Science:

Biomedical Engineering
Dermatology
Pharmaceutical Sciences

Background:

Microneedle technology facilitates transdermal drug delivery by creating microchannels in the skin's stratum corneum.
This approach is particularly promising for delivering large biomolecules such as proteins and peptides, which are challenging via conventional methods.

Purpose of the Study:

To review the latest advancements in microneedle technology, focusing on device design, fabrication, and therapeutic applications.
To discuss the potential of microneedles for enhanced drug and vaccine delivery, as evidenced by recent patents and research.

Main Methods:

Literature review of patents and research articles on microneedle technology.
Analysis of device design, fabrication materials, formulation strategies, and safety considerations.

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Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

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Fabrication and Characterization of Microneedle Patches for Loading and Delivery of Exosomes

Fabrication and Characterization of Microneedle Patches for Loading and Delivery of Exosomes

Published on: July 12, 2024

Main Results:

Microneedles offer a minimally invasive method for transdermal delivery, minimizing pain and bleeding.
The technology is being explored for diverse applications beyond traditional drug and vaccine delivery.
Combinations of microneedles with other enhancement techniques are gaining attention.

Conclusions:

Microneedle technology shows significant potential for revolutionizing transdermal drug delivery, especially for biopharmaceuticals.
Challenges in commercialization, including safety and regulatory aspects, require further attention.
Continued research and development are crucial for the widespread adoption of microneedle-based medical devices.