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Related Concept Videos

Accessory Structures of the Skin: Hair Growth and Types01:20

Accessory Structures of the Skin: Hair Growth and Types

Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
Skin Diseases and Disorders01:23

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Multipotency and Niche of Bulge Stem Cell

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Accessory Structures of the Skin: Hair and Hair Follicles01:16

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Unrenewable Cells00:50

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Related Experiment Video

Updated: Jun 3, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

Alopecia areata.

Kam-Lun E Hon1, Alexander K C Leung

  • 1Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. ehon@hotmail.com

Recent Patents on Inflammation & Allergy Drug Discovery
|April 2, 2011
PubMed
Summary
This summary is machine-generated.

Alopecia areata (AA) is an autoimmune skin condition causing patchy hair loss. While some cases resolve spontaneously, treatments like topical corticosteroids, minoxidil, and novel therapies offer hope for persistent or distressing disease.

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Area of Science:

  • Dermatology
  • Autoimmune Diseases
  • Trichology

Background:

  • Alopecia areata (AA) is an autoimmune condition characterized by nonscarring hair loss.
  • It affects approximately 1.7% of the population, often with onset before age 20.
  • AA typically presents as sudden, localized patches of hair loss on the scalp.

Purpose of the Study:

  • To review the clinical presentation and management of alopecia areata.
  • To discuss current and emerging treatment options for AA.
  • To highlight recent advancements and patents in AA treatment.

Main Methods:

  • Literature review of alopecia areata.
  • Analysis of clinical presentation and diagnostic features.
  • Evaluation of existing and novel therapeutic strategies.

Main Results:

  • AA presents with distinct patches of hair loss, sometimes with "exclamation point hairs."
  • Spontaneous recovery occurs, leading to a "watch-and-wait" approach for some patients.
  • Topical corticosteroids, minoxidil, IL-31 antibodies, and Excimer laser are key treatments.

Conclusions:

  • Alopecia areata requires a nuanced management approach, balancing observation with active treatment.
  • Novel therapies show promise for managing this distressing condition.
  • Continued research and patent activity indicate ongoing advancements in AA treatment.