Historical review of Haller's cells

Area of Science:

• Anatomy
• Otolaryngology
• Medical History

Background:

• Albrecht von Haller first described infraorbital ethmoid cells in 1743.
• This historical study examines the evolving terminology and understanding of Haller's cells.
• The research investigates their role in the development of acute rhinosinusitis.

Discussion:

• Haller's cells have been studied across three distinct historical periods.
• Their pathological influence on acute rhinosinusitis became evident in the mid-20th century.
• These cells may narrow the ethmoidal infundibulum and obstruct the maxillary sinus ostium.

Key Insights:

• The term "Haller's cell" is proposed to specifically denote the inferior ethmoid cell.
• This cell is anatomically located nearest to the maxillary sinus ostium.
• Understanding Haller's cells is crucial for rhinosinusitis pathogenesis.

Outlook:

• Further research can refine the anatomical definition of Haller's cells.
• Clarifying the definition aids in understanding their contribution to rhinosinusitis.
• This historical perspective provides a foundation for future clinical and anatomical studies.