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Updated: Jun 3, 2026
Bead Based Multiplex Assay for Analysis of Tear Cytokine Profiles
Published on: October 13, 2017
[Concentration assessment of interleukin 8 in serum at children with uveitis]
Beata Zelazowska-Rutkowska1, Małgorzata Mrugacz, Jolanta Wysocka
1Z Zakładu Laboratoryjnej Diagnostyki Pediatrycznej Uniwersytetu Medycznego w Białymstoku. zelazowskab@wp.pl
Purpose:
Uveitis in children is a visual threatening disease with a complication rate of more than 75%. At the children the uveitis differs in several aspect from adults like: clinical presentation or complication of disease. The etiology of uveitis is still unknown, but T lymphocytes are generally key mediators of the pathogenesis of uveitis. In our study we evaluate IL-8 concentration in serum in uveitis patients.
Material And Methods:
Serum sample were collected from 28 uveitis patients and 20 people from control group. The level IL-8 was measured with specific enzyme- linked immunoassays ELISA methods (R & D Systems).
Results:
Level of IL-8 in uveitis group was a significant higher (p<0.04) compared with control group.
Conclusions:
Increased levels of interleukin 8 in serum of children with uveitis may suggest innate immune mechanisms in the acute disease.
