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02:28
Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Psoriasis and hypertension severity: results from a case-control study
April W Armstrong1, Steven W Lin, Cynthia J Chambers
1Department of Dermatology, University of California Davis, Sacramento, California, United States of America. aprilarmstrong@post.harvard.edu
Plos One
|April 12, 2011
Summary
Patients with psoriasis often have more difficult-to-manage hypertension. This study found psoriasis patients require more anti-hypertensive medications compared to those without psoriasis.
Area of Science:
- Cardiovascular epidemiology
- Dermatology
- Hypertension management
Background:
- Psoriasis is linked to cardiovascular diseases.
- Hypertension frequency in psoriasis patients has been studied.
- Hypertension severity in relation to psoriasis is not well-characterized.
Purpose of the Study:
- To determine if psoriasis patients have more difficult-to-manage hypertension.
- To compare hypertension management in psoriatic versus non-psoriatic patients.
Main Methods:
- Case-control study utilizing electronic medical records.
- Cases: patients with psoriasis and hypertension.
- Controls: patients with hypertension but without psoriasis.
- 835 cases matched to 2418 controls on age, sex, and BMI.
Main Results:
- Psoriasis significantly associated with multiple anti-hypertensives (p < 0.0001).
- Psoriasis patients were more likely to be on monotherapy (5x), dual (9.5x), triple (16.5x), or quadruple/central therapy (19.9x).
- Adjusted for diabetes, hyperlipidemia, and race.
Conclusions:
- Psoriasis patients exhibit more challenging-to-control hypertension.
- This suggests a need for tailored cardiovascular risk management in psoriasis patients.
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