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Updated: Jun 2, 2026
Plasma Polishing as a New Polishing Option to Reduce the Surface Roughness of Porous Titanium Alloy for 3D Printing
Published on: April 28, 2023
Osteoblastlike cell adhesion on titanium surfaces modified by plasma nitriding
Jose Sandro Pereira da Silva1, Sandro Campos Amico, Almir Olegario Neves Rodrigues
1Departamento de Odontologia, Universidade Federal do Rio Grande do Norte, Natal/RN, Brazil. jspsilva@gmail.com
Purpose:
The aim of this study was to evaluate the characteristics of various titanium surfaces modified by cold plasma nitriding in terms of adhesion and proliferation of rat osteoblastlike cells.
Materials And Methods:
Samples of grade 2 titanium were subjected to three different surface modification processes: polishing, nitriding by plasma direct current, and nitriding by cathodic cage discharge. To evaluate the effect of the surface treatment on the cellular response, the adhesion and proliferation of osteoblastlike cells (MC3T3) were quantified and the results were analyzed by Kruskal-Wallis and Friedman statistical tests. Cellular morphology was observed by scanning electron microscopy.
Results:
There was more MC3T3 cell attachment on the rougher surfaces produced by cathodic cage discharge compared with polished samples (P < .05).
Conclusions:
Plasma nitriding improves titanium surface roughness and wettability, leading to osteoblastlike cell adhesion.
